The Crimson Stain Mystery 1916

Synopsis:

In attempting to develop a chemical which would make a person super-intelligent, Dr. Montrose fails and the subjects of his experiments metamorphose into hideous monsters who band together and prey on humans. With the police stymied, a young detective attempts to track down the leader of the group of killers, known only to have a small crimson stain in one eye.

Directed by: T. Hayes Hunter
Written by: Albert Payson Terhune
Runtime: 355 minutes
Cast:
Maurice Costello
Maurice Costello
Harold Stanley 
Ethel Grandin
Ethel Grandin
Florence Montrose 
Thomas J. McGrane
Thomas J. McGrane
Dr. Burton Montrose 
Olga Olonova
Olga Olonova
Vanya Tosca 
William Cavanaugh
William Cavanaugh
Doctor's Assistant 
John A. Milton
John A. Milton
Layton Parrish (as John Milton) 
Links:
IMDb The Crimson Stain Mystery movie stills
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Also known as:
  • Mancha de Sangue