Evelyn Vail (Florence Rice) is a nurse convicted of poisoning a patient. Out on parole, Evelyn decides to fly to Sing-Sing and confront death row inmate who accused her of the deed in the first place. On board the airliner, Evelyn makes the acquaintance of John Robinson Gordon (Nagel), who is transporting a revolutionary munitions formula to Washington, D.C. Another passenger, Baker (Robert Allen), complains of having been poisoned and leaves the plane during a stopover in Dallas. Back in the air, Gordon's bodyguard, Lieutenant O'Brien (Fred Kelsey), suffers the same fate, but this time the poison proves fatal. The plane returns to Dallas, where Police Captain Barrie (William B. Davidson) accused poor Evelyn of the crime. Happily, Gordon can prove otherwise and the real culprit is unmasked.

Directed by: Phil Rosen
Written by: Fred Niblo Jr. & Albert DeMond
Runtime: 65 minutes
Cast:
William B. Davidson William B. Davidson
Police Captain Barrie 
Fred Kelsey Fred Kelsey
Police Lieutenant O'Brien 
Purnell Pratt Purnell Pratt
Dr. Landers 
Raymond Walburn Raymond Walburn
Evans 
Conrad Nagel Conrad Nagel
John Robinson Gordon