The mega-corporate Daedalus Group is under attack by a small group of activists known as the Ghost of Icarus. While taking care of some of the victims of the bombing, Black Jack encounters Dr. Kiriko, also known as Death Incarnate, who just like him, asks his patients huge sums of money but instead of saving them, he offers them a painless death. When the activist group requests both doctors’ collaboration, Black Jack finds himself caught in a spiral of life, death and treason while trying to save his patients' lives and avoid the breaking of a biological war that could destroy humanity.

Directed by: Satoshi Kuwabara & Makoto Tezuka
Written by: Hirotoshi Kobayashi & Katsuhiko Chiba
Release date: 2005-12-17
Runtime: 97 minutes
Cast:
Akio Otsuka Akio Otsuka
Black Jack (voice) 
Yuko Mizutani Yuko Mizutani
Pinoko (voice) 
Makoto Ishii Makoto Ishii
Largo (voice) 
Kenji Utsumi Kenji Utsumi
Inspector Tomobiki (voice) 
Aya Hirayama Aya Hirayama
Midori (voice) 
Yuma Ishigaki Yuma Ishigaki
Rock (voice) 
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Also known as:
  • The Two Doctors of Darkness
  • Black Jack: The Two Doctors of Darkness
  • BlackJack: The Two Doctors of Darkness
  • Black Jack: The Two Doctors in Black
  • Black Jack: Zwei schwarze Ärzte
  • Black Jack: Os Dois Médicos de Negro